Benemid and Mycophenolate Mofetil Tablets

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using mycophenolate mofetil together with probenecid may increase the effects of mycophenolate mofetil. Contact your doctor if you experience increased side effects or if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Animal studies have shown that coadministration with probenecid results in a 2-fold increase in the systemic exposure (AUC) of mycophenolic acid and a 3-fold increase in the AUC of mycophenolic acid glucuronide, an inactive metabolite. The proposed mechanism is competition of these agents for renal tubular secretion.

MANAGEMENT: Caution is advised if mycophenolic acid products must be used concomitantly with probenecid. The dosage of one or both drugs may require adjustments.

Benemid

Generic Name: probenecid

Brand name: Benemid

Synonyms: n.a.

What is Benemid?

Mycophenolate Mofetil Tablets

Generic Name: mycophenolate mofetil

Brand name: Cellcept, Myfortic, MMF

Synonyms: Mycophenolate mofetil (oral/injection), Mycophenolate

What is Mycophenolate Mofetil Tablets?