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Benemid and Up and Up Acid Controller Complete

Determining the interaction of Benemid and Up and Up Acid Controller Complete and the possibility of their joint administration.

Check result:
Benemid <> Up and Up Acid Controller Complete
Relevance: 19.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Probenecid may inhibit the tubular secretion of famotidine and thereby increase its pharmacologic effects. The clinical significance of this interaction is uncertain.

References
  • Inotsume N, Nishimura M, Nakano M, Fujiyama S, Sato T "The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers." J Clin Pharmacol 30 (1990): 50-6
Benemid

Generic Name: probenecid

Brand name: Benemid

Synonyms: n.a.

Up and Up Acid Controller Complete

Generic Name: calcium carbonate / famotidine / magnesium hydroxide

Brand name: Dual Action Complete, Duo Fusion, Pepcid Complete

Synonyms: Berkley and Jensen Acid Controller Complete

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle