Benzoyl peroxide and clindamycin Topical application and Dapsone topical
Determining the interaction of Benzoyl peroxide and clindamycin Topical application and Dapsone topical and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In one clinical study, topical application of dapsone followed by benzoyl peroxide in subjects with acne vulgaris was associated with a temporary local yellow or orange discoloration of the skin and facial hair in 7 out of 95 subjects, with resolution in 4 to 57 days. The mechanism of interaction is unknown.
- "Product Information. Aczone (dapsone topical)." QLT USA, Inc, Fort Collins, CO.
Generic Name: benzoyl peroxide / clindamycin topical
Brand name: Acanya, Benzaclin, DUAC, Neuac, Onexton, Z-Clinz 10, Z-Clinz 5, BenzaClin with pump, Duac Care System
Synonyms: Benzoyl peroxide and clindamycin topical, Clindamycin and Benzoyl Peroxide
Generic Name: dapsone topical
Brand name: Aczone
Synonyms: Dapsone (Topical)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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