Berinert and Kinlytic

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

C1 esterase inhibitor, human and urokinase may form a complex with each other in the blood, resulting in the deactivation of both medications. Ideally, these medications should not be used together. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: C1 esterase inhibitors inhibit proteases in the coagulation/fibrinolytic system and may inhibit tissue plasminogen activators (tPAs). Complexation of C1 esterase inhibitor and tPA has been observed in scientific studies. However, the interaction has not been studied during clinical use of these agents concomitantly.

MANAGEMENT: Simultaneous administration of a C1 esterase inhibitor and a tPA should preferably be avoided.

Berinert

Generic Name: C1 esterase inhibitor (human)

Brand name: Berinert, Cinryze, Haegarda, Ruconest

Synonyms: n.a.

What is Berinert?

Kinlytic

Generic Name: urokinase

Brand name: Kinlytic, Abbokinase, Abbokinase Open-Cath

Synonyms: n.a.

What is Kinlytic?