Betamethasone and calcipotriene topical and Canakinumab Subcutaneous

• Generic Name: betamethasone / calcipotriene topical
• Dosage Forms: n.a.
• Other Brand Names: Enstilar, Taclonex, Taclonex Scalp, Dovobet

Betamethasone is a steroid. It prevents the release of substances in the body that cause inflammation.

Calcipotriene is a form of vitamin D. It works by decreasing the rate of skin cell reproduction.

Betamethasone and calcipotriene topical (for the skin) is a combination medicine used to treat plaque psoriasis.

Adults may use the suspension (liquid) form of betamethasone and calcipotriene on the skin or the scalp. The liquid may be used only on the scalp in children who are at least 12 years old.

Betamethasone and calcipotriene topical foam or ointment should be used only on the skin and only by adults.

Betamethasone and calcipotriene may also be used for purposes not listed in this medication guide.

• Generic Name: canakinumab
• Dosage Forms: n.a.
• Other Brand Names: Ilaris

Canakinumab injection is used to treat cryopyrin-associated periodic syndromes (CAPS). This also includes familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). CAPS is a rare, inherited disease of the immune system. It occurs when the body produces too much of a chemical called interleukin-1 beta. This chemical causes inflammation, and patients with CAPS may have a fever, headache, skin rash, joint or muscle pain, or unusual tiredness or weakness.

Canakinumab helps prevent inflammation by keeping the interleukin-1 beta from working properly. Canakinumab also treats adults and children with other autoinflammatory periodic fever syndromes, such as tumor necrosis factor receptor associated periodic syndrome (TRAPS), hyperimmunoglobulin D syndrome (HIDS)/mevalonate kinase deficiency (MKD), and familial Mediterranean fever (FMF).

Canakinumab is also used to treat active systemic juvenile idiopathic arthritis (SJIA) in children 2 years of age and older.

Canakinumab is to be given only by or under the direct supervision of a doctor.