Betaxolol Hydrochloride eent and Flurazepam Hydrochloride

• Generic Name: betaxolol ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Betoptic S, Betoptic

Reduction of elevated intraocular pressure (IOP) in patients with chronic open-angle glaucoma and ocular hypertension. Used alone or in conjunction wth a topical miotic (e.g., pilocarpine), topical dipivefrin, topical epinephrine, and/or a carbonic anhydrase inhibitor.

May be used safely in selected patients with reactive airway disease (e.g., asthma, chronic bronchitis, COPD). (See Respiratory Effects under Cautions.)

• Generic Name: flurazepam
• Dosage Forms: n.a.
• Other Brand Names: Dalmane

Short-term management of insomnia. Has been used effectively for periods up to 4 weeks in duration.

Has been used effectively in individuals with difficulty in falling asleep, nocturnal awakenings, and/or early morning awakening.

May exhibit carryover effect (i.e., more effective on second, third, and fourth nights of use than on first night) because of accumulation of active metabolite. Effect may persist on first and sometimes second night after discontinuance.

Because of long half-life, may be more likely to result in residual sedative effects and in impaired psychomotor and mental performance during continued therapy, although partial tolerance to these effects can occur. Differences among hypnotics in residual and cumulative CNS depressant effects may be particularly important in geriatric patients, those with potentially impaired elimination of the drugs, and those whose job or life-style requires unimpaired intellectual or psychomotor function.