Bethkis Inhalation Solution and Eliglustat Tartrate

• Generic Name: tobramycin
• Dosage Forms: respiratory solution
• Other Brand Names: Bethkis, Kitabis Pak, Tobi, TOBI Podhaler

Bethkis is an antibiotic that is inhaled into the lungs using a nebulizer. This medicine inhalation is used to treat lung infections in patients with cystic fibrosis.

Bethkis is for use in adults and children who are at least 6 years old.

Bethkis may also be used for purposes not listed in this medication guide.

• Generic Name: eliglustat
• Dosage Forms: n.a.
• Other Brand Names: Cerdelga

Long-term treatment of nonneuronopathic (type 1) Gaucher disease in patients who are extensive, intermediate, or poor metabolizers of CYP2D6.

Patient selection and dosing based on CYP2D6 metabolizer status; determine patient's CYP2D6 genotype with an FDA-cleared test prior to initiating therapy.

Ultrarapid CYP2D6 metabolizers may not achieve adequate plasma concentrations to achieve a therapeutic effect. A specific dosage cannot be recommended for patients whose CYP2D6 genotype cannot be determined (indeterminate metabolizers).

Designated an orphan drug by FDA for treatment of type 1 Gaucher disease.