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Bevyxxa and Coagulation factor X

Determining the interaction of Bevyxxa and Coagulation factor X and the possibility of their joint administration.

Check result:
Bevyxxa <> Coagulation factor X
Relevance: 02.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Betrixaban may counteract the effects of coagulation factor X. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Based on their mechanisms of action, the pharmacologic activity of coagulation factor X is likely to be counteracted by direct and indirect factor Xa inhibitors. In vivo, factor X is converted from its inactive form to the active form, factor Xa, by the cleavage of a 52-residue peptide from the heavy chain.

MANAGEMENT: Concomitant use of coagulation factor X with direct and indirect factor Xa inhibitors should be avoided.

References
  • "Product Information. Coagadex (coagulation factor X)." Bio Products Laboratory, Raleigh, NC.
Bevyxxa

Generic Name: betrixaban

Brand name: Bevyxxa

Synonyms: n.a.

Coagulation factor X

Generic Name: coagulation factor x

Brand name: Coagadex

Synonyms: Factor X (Human)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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