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Biaxin and Diflucan

Determining the interaction of Biaxin and Diflucan and the possibility of their joint administration.

Check result:
Biaxin <> Diflucan
Relevance: 17.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Fluconazole may increase plasma concentrations of clarithromycin when coadministered. The mechanism of the interaction is unknown. The clinical significance of the elevation appears to be minimal in healthy subjects. Observation for clarithromycin adverse effects is recommended if these drugs are given together.

References
  • Gustavson LE, Shi H, Palmer RN, Siepman NC, Craft JC "Drug interactions between claarithromycin and fluconazole in healthy subjects." Clin Pharmacol Ther 59 (1996): 185
Biaxin

Generic Name: clarithromycin

Brand name: Biaxin, Biaxin XL

Synonyms: Biaxin (Oral Suspension)

Diflucan

Generic Name: fluconazole

Brand name: Diflucan

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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