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Biaxin Filmtab and Nexium 24HR (Esomeprazole Delayed-Release Capsules)

Determining the interaction of Biaxin Filmtab and Nexium 24HR (Esomeprazole Delayed-Release Capsules) and the possibility of their joint administration.

Check result:

Biaxin Filmtab <> Nexium 24HR (Esomeprazole Delayed-Release Capsules)

Relevance: 22.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Clarithromycin may increase the plasma concentration of esomeprazole. The mechanism may be related to clarithromycin inhibition of hepatic cytochrome P450 enzymes responsible for esomeprazole metabolism. The systemic exposure (AUC) to esomeprazole doubled after coadministration with clarithromycin 500 mg twice daily. The clinical significance is unknown and dose adjustments are not required.

References

Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Biaxin Filmtab

Generic Name: clarithromycin

Brand name: Biaxin, Biaxin XL

Synonyms: Biaxin (Oral Suspension), Biaxin

What is Biaxin Filmtab?

Nexium 24HR (Esomeprazole Delayed-Release Capsules)

Generic Name: esomeprazole

Brand name: NexIUM 24HR, Esomeprazole Strontium, Nexium, Nexium, Nexium IV

Synonyms: NexIUM 24HR (Esomeprazole Delayed-Release Tablets)

What is Nexium 24HR (Esomeprazole Delayed-Release Capsules)?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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