Bictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide Fumarate and Engerix-B

• Generic Name: bictegravir / emtricitabine / tenofovir alafenamide
• Dosage Forms: n.a.
• Other Brand Names: Biktarvy

Treatment of HIV-1 infection in antiretroviral-naive (have not previously received antiretroviral therapy) or antiretroviral-experienced (previously treated) adults.

Fixed combination of BIC/FTC/TAF used alone as a complete regimen for treatment of HIV-1 infection; concomitant use with other antiretrovirals not recommended.

For initial treatment in antiretroviral-naive adults, experts state BIC/FTC/TAF is a recommended INSTI-based regimen for most adults.

For antiretroviral-experienced adults, manufacturer states BIC/FTC/TAF can be used to replace the current antiretroviral regimen in those with plasma HIV-1 RNA levels <50 copies/mL on a stable antiretroviral regimen for ≥3 months who have no history of treatment failure and are infected with HIV-1 with no known substitutions associated with resistance to the antiretroviral components of the fixed combination (i.e., bictegravir, emtricitabine, tenofovir).

• Generic Name: hepatitis b adult vaccine
• Dosage Forms: n.a.
• Other Brand Names: Engerix-B, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Heplisav-B

Engerix-B vaccine is used to help prevent hepatitis B in adults.

Hepatitis is a serious disease caused by a virus. Hepatitis causes inflammation of the liver, and may cause vomiting, and jaundice (yellowing of the skin or eyes). Hepatitis can lead to liver cancer, cirrhosis, or death. Hepatitis can also cause no symptoms.

Hepatitis B is a disease of the liver that is spread through blood or bodily fluids, sexual contact or sharing IV drug needles with an infected person, or during childbirth when the mother is infected.

Engerix-B works by exposing you to a small amount of the virus, which causes the body to develop immunity to the disease. Engerix-B will not treat an active infection that has already developed in the body.

Vaccination with hepatitis B adult vaccine is recommended for all adults who are at risk of getting hepatitis B. Risk factors include: having more than one sex partner; being a homosexual male; having sexual contact with infected people; having chronic liver disease; having diabetes and being under age 60; having HIV or AIDS; using intravenous (IV) drugs; being on dialysis or receiving blood transfusions; working in an institution for developmentally disabled patients; working in healthcare or public safety and being exposed to human blood; being in the military or traveling to high-risk areas; and living with a person who has hepatitis B.

Like any vaccine, the Engerix-B may not provide protection from disease in every person.