Bictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide Fumarate and PCM-LA

• Generic Name: bictegravir / emtricitabine / tenofovir alafenamide
• Dosage Forms: n.a.
• Other Brand Names: Biktarvy

Treatment of HIV-1 infection in antiretroviral-naive (have not previously received antiretroviral therapy) or antiretroviral-experienced (previously treated) adults.

Fixed combination of BIC/FTC/TAF used alone as a complete regimen for treatment of HIV-1 infection; concomitant use with other antiretrovirals not recommended.

For initial treatment in antiretroviral-naive adults, experts state BIC/FTC/TAF is a recommended INSTI-based regimen for most adults.

For antiretroviral-experienced adults, manufacturer states BIC/FTC/TAF can be used to replace the current antiretroviral regimen in those with plasma HIV-1 RNA levels <50 copies/mL on a stable antiretroviral regimen for ≥3 months who have no history of treatment failure and are infected with HIV-1 with no known substitutions associated with resistance to the antiretroviral components of the fixed combination (i.e., bictegravir, emtricitabine, tenofovir).

• Generic Name: chlorpheniramine / methscopolamine / pseudoephedrine
• Dosage Forms: n.a.
• Other Brand Names: DryMax, PCM-LA, Mescolor, Rescon MX, AlleRx Dose Pack, Hista-Vent PSE, Durahist, Amdry-C, Time-Hist QD, AllePak, Rhinaclear, Allergy DN, Pseudo CM TR, Allergy AM-PM Dose Pack, VisRx Dose Pack, Histatab, Dallergy PSE, Coldamine, RelCof DN PSE, ScopoHist

Chlorpheniramine and methscopolamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

PCM-LA is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

PCM-LA will not treat a cough that is caused by smoking, asthma, or emphysema.

PCM-LA may also be used for purposes not listed in this medication guide.