Bictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide Fumarate and Symbicort

• Generic Name: bictegravir / emtricitabine / tenofovir alafenamide
• Dosage Forms: n.a.
• Other Brand Names: Biktarvy

Treatment of HIV-1 infection in antiretroviral-naive (have not previously received antiretroviral therapy) or antiretroviral-experienced (previously treated) adults.

Fixed combination of BIC/FTC/TAF used alone as a complete regimen for treatment of HIV-1 infection; concomitant use with other antiretrovirals not recommended.

For initial treatment in antiretroviral-naive adults, experts state BIC/FTC/TAF is a recommended INSTI-based regimen for most adults.

For antiretroviral-experienced adults, manufacturer states BIC/FTC/TAF can be used to replace the current antiretroviral regimen in those with plasma HIV-1 RNA levels <50 copies/mL on a stable antiretroviral regimen for ≥3 months who have no history of treatment failure and are infected with HIV-1 with no known substitutions associated with resistance to the antiretroviral components of the fixed combination (i.e., bictegravir, emtricitabine, tenofovir).

• Generic Name: budesonide / formoterol
• Dosage Forms: aerosol
• Other Brand Names: Symbicort, Symbicort Turbuhaler, Symbicort 400/12 Turbohaler

Symbicort contains a combination of budesonide and formoterol. Budesonide is a corticosteroid that reduces inflammation in the body. Formoterol is a long-acting bronchodilator that relaxes muscles in the airways to improve breathing.

Symbicort is used to control and prevent the symptoms of asthma in adults and children at least 6 years old.

Symbicort is also used to help control the symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

Symbicort is not for use in treating an asthma or bronchospasm attack.

For people with asthma: Symbicort is for use only if asthma is severe or is not well-controlled on other long-term asthma medicines. Your doctor may tell you to stop using this medicine once your asthma is well-controlled.

Formoterol when used alone may increase the risk of death in people with asthma. However, this risk is not increased when budesonide and formoterol are used together as a combination product.