Bimatoprost and Eslicarbazepine Acetate

• Generic Name: bimatoprost ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Lumigan

Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are intolerant of other IOP-lowering drugs or who have not responded adequately (i.e., failed to achieve target IOP as determined after multiple measurements over time) to another IOP-lowering drug.

Safety and efficacy not established for the treatment of angle-closure, inflammatory, or neovascular glaucoma.

At least as effective as latanoprost 0.005% in controlling diurnal IOP; may be more effective than timolol 0.5% in reducing IOP in patients with open-angle glaucoma or ocular hypertension.

• Generic Name: eslicarbazepine
• Dosage Forms: n.a.
• Other Brand Names: Aptiom

Management (in combination with other anticonvulsants) of partial-onset seizures in adults.

In longer-term extension studies, reductions in seizure frequency were maintained for at least 1 year.

Controlled comparative trials between eslicarbazepine acetate and oxcarbazepine needed to fully evaluate the relative efficacy and tolerability of these structurally related anticonvulsants (see Actions).

Once-daily dosage regimen may help improve patient compliance.