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Bimatoprost topical ophthalmic and Travatan Z

Determining the interaction of Bimatoprost topical ophthalmic and Travatan Z and the possibility of their joint administration.

Check result:
Bimatoprost topical ophthalmic <> Travatan Z
Relevance: 28.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Treatment with bimatoprost topical ophthalmic may interfere with the pressure-lowering effect of travoprost ophthalmic in the eye. Talk to your doctor if you have any questions or concerns. You may need more frequent eye examinations to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: In patients using bimatoprost or other prostaglandin analogs for the treatment of intraocular hypertension, the concomitant use of bimatoprost 0.03% ophthalmic solution to treat hypotrichosis of the eyelashes may interfere with the desired reduction in intraocular pressure (IOP). In clinical trials, bimatoprost 0.03% solution applied topically to the upper eyelid margin lowered IOP in both patients with or without elevated IOP, although the magnitude of the reduction was not cause for clinical concern. In previous studies of bimatoprost for the treatment of ocular hypertension, it has been shown that exposure of the eye to more than one dose of bimatoprost daily may decrease the IOP-lowering effect. Therefore, topical administration of bimatoprost to the eyelid in conjunction with ocular instillation of IOP-lowering prostaglandin analogs may decrease the IOP-lowering effect in ocular hypertensive patients.

MANAGEMENT: Patients using these products concomitantly should be closely monitored for changes to their intraocular pressure.

References
  • "Product Information. Latisse (bimatoprost topical ophthalmic)." Allergan Inc, Irvine, CA.
Bimatoprost topical ophthalmic

Generic Name: bimatoprost topical

Brand name: Latisse

Synonyms: n.a.

Travatan Z

Generic Name: travoprost ophthalmic

Brand name: Travatan, Travatan Z

Synonyms: Travatan Z Ophthalmic Solution

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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