Binosto and Magnesium Sulfate Granules (Epsom Salt)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate. MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 30 minutes after the bisphosphonate dose. References Darcy PF "Nutrient-drug interactions." Adverse Drug React Toxicol Rev 14 (1995): 233-54 "Product Information. Boniva (ibandronate)." Roche Laboratories, Nutley, NJ. "Product Information. Skelid (tilundronate)." Sanofi Winthrop Pharmaceuticals, New York, NY. "Product Information. Bonefos (clodronate)." Rhone-Poulenc Rorer Canada Inc, Laval, QC. "Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH. "Product Information. Fosamax (alendronate)." Merck & Co, Inc, West Point, PA. View all 6 references

ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.

MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 30 minutes after the bisphosphonate dose.

Binosto

Generic Name: alendronate

Brand name: Binosto, Fosamax

Synonyms: n.a.

What is Binosto?

Magnesium Sulfate Granules (Epsom Salt)

Generic Name: magnesium sulfate

Brand name: Epsom Salt

Synonyms: Magnesium sulfate, Magnesium Sulfate

What is Magnesium Sulfate Granules (Epsom Salt)?