Bivalirudin and Indocin Rectal
Determining the interaction of Bivalirudin and Indocin Rectal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using indomethacin together with bivalirudin can cause you to bleed more easily. Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. You may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The safety and efficacy of bivalirudin have not been established when used in conjunction with platelet inhibitors other than aspirin. Theoretically, the concomitant administration of bivalirudin (plus aspirin) and platelet inhibitors may increase the risk of bleeding complications due to additive or synergistic effects on the clotting cascade. However, limited data from drug interaction studies do not suggest pharmacodynamic interactions with the platelet inhibitors, ticlopidine and abciximab.
MANAGEMENT: Until further data are available, the coadministration of bivalirudin and antiplatelet agents, and possibly other agents with antiplatelet activity such as nonsteroidal anti-inflammatory drugs (NSAIDs), should probably be undertaken with caution. Close clinical and laboratory observation for bleeding complications is recommended.
- "Product Information. Angiomax (bivalirudin)" The Medicines Compny, Cambridge, MA.
Generic Name: indomethacin
Brand name: Indocin, Indocin SR, Tivorbex
Synonyms: Indocin, Indocin Suppository
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bivalirudin-Indocin SR
- Bivalirudin-Indocin Suppository
- Bivalirudin-Indocin Suspension
- Bivalirudin-Indocyanine Green
- Bivalirudin-Indocyanine green Intravenous
- Bivalirudin-Indomethacin
- Indocin Rectal-Bivalirudin Intravenous
- Indocin Rectal-Bivigam
- Indocin Rectal-Black Cohosh
- Indocin Rectal-Black Draught
- Indocin Rectal-Blenoxane
- Indocin Rectal-Bleo 15k