Bivigam and Dinutuximab

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

The use of immune globulin intravenous may decrease the effectiveness of dinutuximab. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications your use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Concomitant use of dinutuximab beta with intravenous immunoglobulin may lead to a reduction in the dose-dependent cytotoxic effects of dinutuximab beta. The mechanism has not been elucidated; however, it may relate to the effects of antibodies in immunoglobulin on the antibody dependent cell-mediated cellular cytotoxic effects of dinutuximab beta. Clinical data are not available. The interaction may also occur with dinutuximab. Clinical data are not available for intravenous immunoglobulin or for immunoglobulins administered via the intramuscular or subcutaneous routes.

MANAGEMENT: The manufacturer of dinutuximab beta recommends that concomitant use with intravenous immunoglobulins should be avoided (UK). If concomitant use is required, close clinical and laboratory monitoring for treatment efficacy is recommended both during and after discontinuation of therapy.

Bivigam

Generic Name: immune globulin intravenous

Brand name: Bivigam, Carimene N/F, Flebogamma DIF, Gammaplex, Octagam Gammagard S/D, Gammagard S/D, Sandoglobulin, Venoglobulin-S 5%, Venoglobulin-S 10%, Gammar IV, Gammar-P IV, Iveegam, Polygam S/D, Gamimune N 5%, Gamimune N 10%, Panglobulin, Iveegam EN, Gamunex, Panglobulin NF, Gammagard, Panzyga

Synonyms: n.a.

What is Bivigam?

Dinutuximab

Generic Name: dinutuximab

Brand name: Unituxin

Synonyms: n.a.

What is Dinutuximab?