Black Cohosh and Cisplatin Intravenous

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using CISplatin together with black cohosh. Using these medications together can make CISplatin less effective. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Preliminary data from an animal model suggest that black cohosh (Cimicifuga racemosa rhizome) may reduce the cytotoxic effect of cisplatin on breast cancer cells. Mouse mammary tumor cells exposed to a high concentration of black cohosh (Cimicifuga racemosa rhizome) (100 times the recommended dose) were found to be slightly more resistant to cisplatin than were cells treated with cisplatin alone or cisplatin plus vehicle. The clinical significance in humans is unknown.

MANAGEMENT: Until more data are available, investigators of the study suggest that patients with breast cancer be discouraged from taking black cohosh (Cimicifuga racemosa rhizome).

Black Cohosh

Generic Name: black cohosh

Brand name:

Synonyms: n.a.

What is Black Cohosh?

Cisplatin Intravenous

Generic Name: cisplatin

Brand name: Platinol, Platinol-AQ

Synonyms: Cisplatin, CISplatin

What is Cisplatin Intravenous?