Bontril PDM and Cangrelor tetrasodium

• Generic Name: phendimetrazine
• Dosage Forms: n.a.
• Other Brand Names: Bontril PDM, Bontril, Melfiat

• It is used to treat obesity.

• Generic Name: cangrelor
• Dosage Forms: n.a.
• Other Brand Names: Kengreal

Used as an adjunct to PCI to reduce the risk of periprocedural MI, repeat coronary revascularization, and stent thrombosis in patients who have not been treated with a P2Y12-receptor antagonist and are not being given a glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitor.

Dual-drug antiplatelet therapy with a P2Y12-receptor antagonist and aspirin is part of the current standard of care in patients with acute coronary syndromes (ACS).

Potential advantages of cangrelor include rapid onset and offset of effect and less interindividual variability in antiplatelet effect (i.e., compared with clopidogrel).

Precise role of cangrelor in the management of ACS remains to be established.