Bortezomib Intravenous and Valdecoxib

• Generic Name: bortezomib
• Dosage Forms: n.a.
• Other Brand Names: Velcade

Bortezomib injection is used to treat multiple myeloma (blood plasma cell cancer) in patients with or without a prior history of treatment, and mantle cell lymphoma.

Bortezomib is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal body cells may also be affected by bortezomib, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, such as a skin rash, may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.

Bortezomib is to be given only by or under the supervision of your doctor.

• Generic Name: valdecoxib
• Dosage Forms: n.a.
• Other Brand Names:

Valdecoxib is a non-steroidal anti-inflammatory drug. Nonsteroidal anti-inflammatory drugs (also called NSAIDs) are used to relieve some symptoms caused by arthritis (rheumatism), such as inflammation, swelling, stiffness, and joint pain. However, valdecoxib does not cure arthritis and will help you only as long as you continue to take it. It may also be used to treat pain associated with menstrual periods.

Valdecoxib was available only with your doctor's prescription.

Valdecoxib was voluntarily withdrawn from the U.S. market on April 7, 2005 due to safety concerns of increased risk of serious heart problems and skin reactions .