Botox and Sublimaze

• Generic Name: onabotulinumtoxinA
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Botox, Botox Cosmetic

Botox (onabotulinumtoxinA) is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles.

Botox is used to treat cervical dystonia (severe spasms in the neck muscles) in adults; muscle stiffness in the elbows, wrists, and fingers in adults and children 2 to 17 years of age with upper limb spasticity; and muscle stiffness in the ankles or toes in adults and children 2 to 17 years of age with lower limb spasticity. It is also used to treat severe underarm sweating (hyperhidrosis).

Botox is also used in adults to treat overactive bladder, and incontinence (urine leakage) caused by nerve disorders such as spinal cord injury or multiple sclerosis.

Botox is also used in adults to prevent chronic migraine headaches in adults who have migraines for more than 15 days per month, each lasting 4 hours or longer. This medicine should not be used to treat a common tension headache.

Botox is also used to treat certain eye muscle conditions caused by nerve disorders in adults and children who are at least 12 years old. This includes uncontrolled blinking or spasm of the eyelids (blepharospasm), and a condition in which the eyes do not point in the same direction (strabismus).

Botox Cosmetic is used to temporarily lessen the appearance of facial wrinkles in adults.

• Generic Name: fentanyl
• Dosage Forms: injection
• Other Brand Names: Sublimaze, Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Lazanda, Onsolis

• It is used to ease pain.