Bretylium and Norpace

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using bretylium and disopyramide is not recommended. Taking these drugs together can affect the rhythm of your heart. Call your doctor if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: Like other class III antiarrhythmic agents, bretylium can cause dose-related QT interval prolongation. Theoretically, coadministration with other agents that can prolong the QT interval such as disopyramide may result in elevated risk of ventricular arrhythmias, including ventricular tachycardia and torsade de pointes, because of additive arrhythmogenic potential related to their effects on cardiac conduction.

MANAGEMENT: Concomitant use of disopyramide with class III antiarrhythmic agents is not recommended by the manufacturer.

Bretylium

Generic Name: bretylium

Brand name:

Synonyms: Bretylium Injection

What is Bretylium?

Norpace

Generic Name: disopyramide

Brand name: Norpace, Norpace CR

Synonyms: n.a.

What is Norpace?