Brevibloc Premixed and Ivabradine Oral Solution
Determining the interaction of Brevibloc Premixed and Ivabradine Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Both ivabradine and esmolol can slow the heart rate, and using them together may increase this effect and cause conduction problems and irregular heart rhythm. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if you develop significant decreases in heart rate or symptoms such as dizziness, lightheadedness, fainting, or low blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of ivabradine with other drugs that can slow the heart rate such as beta-blockers, calcium channel blockers, and digitalis may increase the risk of excessive bradycardia or other conduction disturbances. Non-cardiac drugs that may also cause bradycardia include atazanavir, fingolimod, lacosamide, lithium, mefloquine, succinylcholine, thalidomide, H2-receptor antagonists, tricyclic antidepressants, and anticholinesterase or cholinergic agents.
MANAGEMENT: Caution is advised when ivabradine is prescribed with other bradycardic drugs. Heart rate should be closely monitored, and the dosage of ivabradine adjusted accordingly. Patients should be advised to report significant decreases in heart rate or symptoms such as dizziness, lightheadedness, fatigue, and hypotension.
- "Product Information. Corlanor (ivabradine)." Amgen USA, Thousand Oaks, CA.
Generic Name: esmolol
Brand name: Brevibloc
Synonyms: Brevibloc
Generic Name: ivabradine
Brand name: Corlanor
Synonyms: Ivabradine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Brevibloc Premixed-Ivabradine Tablets
- Brevibloc Premixed-Ivacaftor
- Brevibloc Premixed-Ivacaftor and lumacaftor
- Brevibloc Premixed-Ivacaftor and tezacaftor
- Brevibloc Premixed-Ivacaftor Granules
- Brevibloc Premixed-Ivacaftor Tablets
- Ivabradine Oral Solution-Brevibloc Premixed DS
- Ivabradine Oral Solution-Brevicon
- Ivabradine Oral Solution-Brevital Sodium
- Ivabradine Oral Solution-Brevoxyl (Benzoyl Peroxide Gel)
- Ivabradine Oral Solution-Brevoxyl (Benzoyl Peroxide Lotion)
- Ivabradine Oral Solution-Brevoxyl Acne Wash Kit