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Brevital Sodium and Clonidine Extended-Release Tablets

Determining the interaction of Brevital Sodium and Clonidine Extended-Release Tablets and the possibility of their joint administration.

Check result:
Brevital Sodium <> Clonidine Extended-Release Tablets
Relevance: 14.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Limited data indicate that premedication with clonidine significantly reduces the dose of thiamylal required to induce anesthesia. Data are available from pediatrics, and are theoretically applicable to thiopental and methohexital, which are related compounds.

References
  • Nishina K, Mikawa K, Maekawa N, Takao Y, Obara H "Clonidine decreases the dose of thiamylal required to induce anesthesia in children." Anesth Analg 79 (1994): 766-8
Brevital Sodium

Generic Name: methohexital

Brand name: Brevital Sodium

Synonyms: n.a.

Clonidine Extended-Release Tablets

Generic Name: clonidine

Brand name: Catapres, Kapvay, Catapres-TTS, Duraclon, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3

Synonyms: Clonidine, CloNIDine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.