Brevital Sodium and Griseofulvin Microsize Oral Suspension
Determining the interaction of Brevital Sodium and Griseofulvin Microsize Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using methohexital together with griseofulvin may decrease the effects of griseofulvin. Contact your doctor if your infection worsens. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Barbiturates may decrease serum griseofulvin levels. The mechanism may be related to decreased absorption of griseofulvin. Therapeutic failure has been reported. Phenobarbital and primidone are the only barbiturates specifically implicated in this interaction. However, other barbiturates may behave in a similar fashion.
MANAGEMENT: Patients should be monitored for reduced antifungal efficacy. It may be necessary to increase griseofulvin doses or use alternative therapeutic agents.
- Kraml M, Marton AV, Dvornik D, Chappel C, Garbaczewska L "Effect of primidone (Mysoline) on tissular levels of griseofulvin in the rat." Proc Soc Exp Biol Med 120 (1965): 678-9
- Riegelman S, Rowland M, Epstein WL "Griseofulvin-phenobarbital interaction in man." JAMA 213 (1970): 426-31
- Busfield D, Child KJ, Atkinson RM, Tomich EG "An effect of phenobarbitone on blood-levels of griseofulvin in man." Lancet 2 (1963): 1042-3
Generic Name: methohexital
Brand name: Brevital Sodium
Synonyms: n.a.
Generic Name: griseofulvin
Brand name: Grifulvin V, Fulvicin P/G, Fulvicin U/F, Gris-PEG, Grisactin Ultra, Grisactin 250, Grisactin 500, Griseofulicin, Griseofulvic
Synonyms: Griseofulvin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Brevital Sodium-Griseofulvin Microsize Tablets
- Brevital Sodium-Griseofulvin Tablets
- Brevital Sodium-Griseofulvin Ultramicrosize Tablets
- Brevital Sodium-Guaiatussin AC
- Brevital Sodium-Guaifen DAC
- Brevital Sodium-Guaifenesin AC Liquid
- Griseofulvin Microsize Oral Suspension-Brevoxyl (Benzoyl Peroxide Gel)
- Griseofulvin Microsize Oral Suspension-Brevoxyl (Benzoyl Peroxide Lotion)
- Griseofulvin Microsize Oral Suspension-Brevoxyl Acne Wash Kit
- Griseofulvin Microsize Oral Suspension-Brevoxyl Creamy Wash
- Griseofulvin Microsize Oral Suspension-Brevoxyl Gel
- Griseofulvin Microsize Oral Suspension-Brevoxyl Topical