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Brilinta Tablets and Novoseven

Determining the interaction of Brilinta Tablets and Novoseven and the possibility of their joint administration.

Check result:

Brilinta Tablets <> Novoseven

Relevance: 11.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Antifibrinolytic agents (e.g., aminocaproic acid or tranexamic acid) and recombinant factor VIIa may increase hemostasis and antagonize the effects of ticagrelor. They may be more effective in managing clinical bleeding events that occur during ticagrelor therapy compared to platelet infusions or desmopressin. No data exist regarding a hemostatic benefit of platelet transfusions in the presence of ticagrelor; circulating ticagrelor may inhibit transfused platelets. Template bleeding time did not decrease when ticagrelor was coadministered with desmopressin; therefore, desmopressin is unlikely to be effective in managing clinical bleeding events. Ticagrelor should be discontinued if active bleeding occurs, and may be resumed after the bleeding has been controlled and the cause identified.

References

"Product Information. Brilinta (ticagrelor)." Astra-Zeneca Pharmaceuticals, Wilmington, DE.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Brilinta Tablets

Generic Name: ticagrelor

Brand name: Brilinta

Synonyms: Brilinta

What is Brilinta Tablets?

Novoseven

Generic Name: coagulation factor viia

Brand name: NovoSeven RT with MixPro, Novoseven, NovoSeven RT

Synonyms: NovoSeven RT with MixPro (injection), NovoSeven RT

What is Novoseven?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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