Brimonidine and Timolol and Crotalidae immune f(ab)2 (equine) Intravenous
Determining the interaction of Brimonidine and Timolol and Crotalidae immune f(ab)2 (equine) Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using timolol ophthalmic together with antivenin (Crotalidae) polyvalent may increase the severity and duration of anaphylactic reactions during the administration of antivenin (Crotalidae) polyvalent. Contact your doctor if you experience increased side effects or if you have any breathing difficulties. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Beta-adrenergic blockers (including ophthalmic formulations) may increase the severity and duration of acute anaphylactic reactions to antivenins. In addition, anaphylaxis may be resistant to the usual treatment modalities. The mechanism is unknown.
MANAGEMENT: Patients should be closely monitored for signs of severe, acute hypersensitivity reactions during administration of antivenins, and facilities and equipment for resuscitation, cardiovascular support, and airway management should be immediately available. Clinicians should be aware that larger doses of epinephrine or other adrenergic agents may be required.
- "Product Information. Antivenin (Latrodectus Mactans) (black widow spider species antivenin)." Merck & Company Inc, West Point, PA.
- "Product Information. Crofab (antivenin (crotalidae) polyvalent)" Savage Laboratories, Melville, NY.
Generic Name: brimonidine / timolol ophthalmic
Brand name: Combigan
Synonyms: Brimonidine and timolol ophthalmic
Generic Name: antivenin (crotalidae) polyvalent
Brand name: Anavip, CroFab, Antivenin Polyvalent
Synonyms: Antivenin (Crotalidae) polyvalent, Crotalidae Immune F(ab')2 (Equine)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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