Brimonidine and timolol ophthalmic and Methacholine
Determining the interaction of Brimonidine and timolol ophthalmic and Methacholine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using timolol ophthalmic and methacholine is not recommended. Taking these drugs together can cause symptoms of chest tightness, difficulity breathing, shortness of breath, or nausea. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:CONTRAINDICATED: Patients who are concurrently receiving beta blockers may have exaggerated or prolonged responses (i.e., bronchoconstriction) to methacholine challenge and may not respond readily to treatment. Beta-2-adrenergic blockade increases airway resistance. Ophthalmically applied beta blockers undergo some systemic absorption and potentially may also interact.
MANAGEMENT: Administration of methacholine to a patient on any beta blocker therapy is considered contraindicated.
- "Product Information. Provocholine (methacholine)." Methapharm Inc, Brantford, ON.
Generic Name: brimonidine / timolol ophthalmic
Brand name: Combigan
Synonyms: Brimonidine and Timolol
Generic Name: methacholine
Brand name: Provocholine
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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