Brimonidine and timolol ophthalmic and Osimertinib Mesylate

• Generic Name: brimonidine / timolol ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Combigan

Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Timolol is a beta-blocker that also reduces pressure inside the eye.

Brimonidine and timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Brimonidine and timolol ophthalmic may also be used for purposes not listed in this medication guide.

• Generic Name: osimertinib
• Dosage Forms: n.a.
• Other Brand Names: Tagrisso

First-line treatment of metastatic NSCLC in patients with epidermal growth factor receptor (EGFR) exon 19 deletions (del19) or exon 21 (L858R) substitution mutations (as detected by an FDA-approved diagnostic test).

Treatment of metastatic NSCLC in patients with EGFR T790M mutation (as detected by an FDA-approved diagnostic test) who have experienced disease progression during or after EGFR tyrosine kinase inhibitor therapy.

Designated an orphan drug by FDA for treatment of EGFR mutation-positive NSCLC.