Brimonidine Tartrate topical and Perflutren lipid microsphere Intravenous

• Generic Name: brimonidine topical
• Dosage Forms: n.a.
• Other Brand Names: Mirvaso, Mirvaso Pump

Used topically for the treatment of persistent (nontransient) erythema associated with rosacea (acne rosacea).

Effective in treating erythema, unlike other currently available medications for rosacea (e.g., azelaic acid, doxycycline, metronidazole).

Does not affect the inflammatory lesions associated with rosacea.

• Generic Name: perflutren
• Dosage Forms: n.a.
• Other Brand Names: Definity, Optison

Perflutren lipid microsphere preparation is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound. Ultrasound is a special kind of diagnostic procedure. It uses high-frequency sound waves to create images or “pictures” of certain areas inside the body. The sound waves produced by the ultrasound equipment can be reflected (bounced off) by different parts of the body, like for example, the heart. As the sound waves return they are electronically converted into images on a television screen. Unlike x-rays, ultrasound does not involve ionizing radiation.

The perflutren lipid microspheres preparation contains very small gas-filled lipid microspheres that reflect the sound waves and help create a better picture. The lipid microsphere preparation is given by injection into a vein before ultrasound to help diagnose problems of the heart.

Perflutren lipid microsphere is to be given only by or under the direct supervision of a doctor with specialized training in ultrasound procedures.