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Brodspec and Collagenase Santyl

Determining the interaction of Brodspec and Collagenase Santyl and the possibility of their joint administration.

Check result:
Brodspec <> Collagenase Santyl
Relevance: 11.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you have received tetracycline within the last 14 days, you should talk to your doctor before receiving collagenase clostridium histolyticum. Using these medications together or within a short time of each other can reduce the effects of collagenase clostridium histolyticum. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: In vitro, tetracycline derivatives inhibit matrix metalloproteinase-mediated collagen degradation. Clinical data are lacking.

MANAGEMENT: It is recommended that collagenase clostridium histolyticum should not be administered to patients who have received tetracycline antibiotics within the previous 14 days.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Brodspec

Generic Name: tetracycline

Brand name: Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap, Tetracon, Robitet 500, Emtet-500

Synonyms: n.a.

Collagenase Santyl

Generic Name: collagenase clostridium histolyticum

Brand name: Xiaflex

Synonyms: Collagenase clostridium histolyticum, Collagenase (Systemic)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction