Bromfenac Sodium and Heparin Lock Flush Solution
Determining the interaction of Bromfenac Sodium and Heparin Lock Flush Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using bromfenac ophthalmic together with heparin may increase the risk of bleeding. Nonsteroidal anti-inflammatory drugs including those in topical preparations such as eye drop and analgesic cream/ointment/gel can interfere with clotting and cause bleeding, especially when used regularly or for prolonged periods. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Systemically and topically administered nonsteroidal anti-inflammatory drugs (NSAIDs) may potentiate the risk of bleeding in patients treated with anticoagulants and other drugs that affect hemostasis such as platelet inhibitors, thrombin inhibitors, thrombolytic agents, or agents that commonly cause thrombocytopenia. The pharmacologic effects of NSAIDs that contribute to this interaction include prolongation of prothrombin time and inhibition of platelet adhesion and aggregation.
MANAGEMENT: Caution is advised if NSAIDs are used in combination with other drugs that affect hemostasis. Close clinical and laboratory observation for hematologic complications is recommended. Patients should be advised to promptly report any signs of bleeding to their doctor, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
- "Product Information. Acular (ketorolac)." Allergan Inc, Irvine, CA.
- "Product Information. Xibrom (bromfenac ophthalmic)." ISTA Pharmaceuticals, Irvine, CA.
- "Product Information. Nevanac (nepafenac ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
Generic Name: bromfenac ophthalmic
Brand name: BromSite, Prolensa, Xibrom, Bromday
Synonyms: Bromfenac (ophthalmic)
Generic Name: heparin
Brand name: Hep-Pak, Heparin Lock flush, Hep-Pak CVC, Hep-Lock, Heparin Sodium ADD-Vantage, HepFlush
Synonyms: Heparin Injection, Heparin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bromfenac Sodium-Heparin Sodium
- Bromfenac Sodium-Heparin, Concentrate
- Bromfenac Sodium-Hepatamine
- Bromfenac Sodium-Hepatasol Injection
- Bromfenac Sodium-Hepatitis A adult vaccine
- Bromfenac Sodium-Hepatitis A and Hepatitis B Recombinant Vaccine
- Heparin Lock Flush Solution-Bromhist PDX
- Heparin Lock Flush Solution-Bromhist-PDX Syrup
- Heparin Lock Flush Solution-Bromo Seltzer
- Heparin Lock Flush Solution-Bromocriptine
- Heparin Lock Flush Solution-Bromocriptine (Cycloset)
- Heparin Lock Flush Solution-Bromocriptine (Parlodel)