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Brompheniramine and phenylephrine and Oxytocin

Determining the interaction of Brompheniramine and phenylephrine and Oxytocin and the possibility of their joint administration.

Check result:

Brompheniramine and phenylephrine <> Oxytocin

Relevance: 04.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using oxytocin together with phenylephrine may cause significant elevations in blood pressure and increase the risk of hypertension. Blood pressure and heart rate should be closely monitored if these medications are used together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Concomitant use of oxytocic agents with sympathomimetic amines may increase the risk of hypertension due to additive vasoconstrictive effects. Severe hypertension and headache have been reported when oxytocin was given 3 to 4 hours following prophylactic administration of a vasoconstrictor in conjunction with caudal block anesthesia.

MANAGEMENT: Close monitoring of blood pressure is recommended during coadministration.

References

"Product Information. Syntocinon (oxytocin)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Brompheniramine and phenylephrine

Generic Name: brompheniramine / phenylephrine

Brand name: Children's Cold & Allergy, Dimaphen Elixir, Dimetapp Cold & Allergy, Rynex PE, Dimetane Decongestant, Bromfenex PE, Bromfenex PE Pediatric, Bromfed, Bromfed-PD Capsules, Rhinabid, VaZol-D, BroveX-D, Rhinabid PD, Alenaze-D, BPM PE, B-Vex D, Bromaphedrine D, Alenaze-D NR, VazoBid, Alacol, J-Tan D, Brom Tann PE, Phenyl 75/6mg, Phenyl 15/12mg, J-Tan D SR, Seradex-LA, Vazotab, BroveX PEB, BroveX ADT, Zotex-PE, Tanabid SR, RespaHist II, V-Hist, Entre-B, LoHist PEB, Brohist D, Ru-Hist D, Relhist BP, Decon-A, BroveX-D, BroveX PB

Synonyms: n.a.

What is Brompheniramine and phenylephrine?

Oxytocin

Generic Name: oxytocin

Brand name: Pitocin, Syntocinon

Synonyms: n.a.

What is Oxytocin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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