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Brompheniramine and Pseudoephedrine Drops and Wakix

Determining the interaction of Brompheniramine and Pseudoephedrine Drops and Wakix and the possibility of their joint administration.

Check result:

Brompheniramine and Pseudoephedrine Drops <> Wakix

Relevance: 01.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.

Professional:

GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.

MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.

Brompheniramine and Pseudoephedrine Drops

Generic Name: dexbrompheniramine / pseudoephedrine

Brand name: Conex, Drixoral Cold and Allergy, Drexophed SR, Desihist SA, Duomine, Dexophed, Disobrom, Disophrol, Drixoral, 12 Hour Cold, Dexaphen SA, Dixaphedrine, Drixomed, Pharmadrine, Ala Hist PE, Ala-Hist PE, Drixoral Sinus

Synonyms: Dexbrompheniramine and pseudoephedrine

What is Brompheniramine and Pseudoephedrine Drops?

Wakix

Generic Name: pitolisant

Brand name: Wakix

Synonyms: Wakix Tablets

What is Wakix?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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