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Brotapp and OnabotulinumtoxinA Cosmetic Injection

Determining the interaction of Brotapp and OnabotulinumtoxinA Cosmetic Injection and the possibility of their joint administration.

Check result:
Brotapp <> OnabotulinumtoxinA Cosmetic Injection
Relevance: 13.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using onabotulinumtoxinA together with brompheniramine may increase certain side effects such as dry mouth, blurred vision, and urinary problems. Let your doctor know if you develop these symptoms during treatment and they do not go away after a few days or they become troublesome. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Use of anticholinergic drugs after administration of botulinum toxin may potentiate systemic anticholinergic effects such as dry mouth, blurred vision, and urinary disorders. Botulinum toxin inhibits the release of acetylcholine from peripheral cholinergic nerve endings, thus additive or synergistic anticholinergic effects may occur when these agents are used together.

MANAGEMENT: Patients should be advised that systemic anticholinergic side effects such as dry mouth, blurred vision, and urinary disorders may increase if agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic antidepressants; disopyramide) are used after administration of botulinum toxin.

References
  • "Product Information. Botox (onabotulinumtoxin A)." Allergan Inc, Irvine, CA.
  • "Product Information. Dysport (abobotulinumtoxinA)." Tercica Inc, Brisbane, CA.
  • "Product Information. Myobloc (botulinum toxin type B)" Elan Pharmaceuticals, S. San Francisco, CA.
  • "Product Information. Xeomin (botulinum toxin type A (obsolete) (botulinum toxin type A))." Merz Pharmaceuticals, Greensboro, NC.
Brotapp

Generic Name: brompheniramine / pseudoephedrine

Brand name: Bromaline, Brotapp, J-TanD PD, Lodrane D, Q-Tapp, Endafed, Touro A&H, Shellcap, Allent, Shellcap PD, Lodrane LD, Bromfed PD, Dallergy JR, Nalfed PD, Respahist, Iofed PD, Ultrabrom PD, Pseubrom-PD, Bromfenex PD, Bromfed, M-Hist TD, Ultrabrom, Iofed, Pseubrom, Bromfenex, Lodrane Liquid, Nalfed, Rondec Chewable, Touro Allergy, Rondec Syrup, Bromfed SR, Histex SR, Rondec, Andehist NR Syrup, Dimetapp Elixir, Bromaxefed RF Syrup, Brofed, Sildec, Bromhist Pediatric Drops, Lodrane 12D, AccuHist Pediatric, AccuHist Drops, Unit-Tex 10/120 ER, Unit-Hist Drops, Di-Bromm, Bromhist-NR, Bidhist-D, Dimaphen, Brovex SR, Lodrane 24D, LoHist-PD, LoHist-12D, B-Vex PD, BroveX PSE, BroveX PD, BroveX PSB, LoHist PSB

Synonyms: n.a.

OnabotulinumtoxinA Cosmetic Injection

Generic Name: onabotulinumtoxinA

Brand name: Botox, Botox Cosmetic

Synonyms: OnabotulinumtoxinA

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle