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Brotapp and Treprostinil Extended-Release Tablets

Determining the interaction of Brotapp and Treprostinil Extended-Release Tablets and the possibility of their joint administration.

Check result:

Brotapp <> Treprostinil Extended-Release Tablets

Relevance: 13.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pseudoephedrine together with treprostinil. Using these medications together can make treprostinil less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References

Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
"Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
"Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.

Brotapp

Generic Name: brompheniramine / pseudoephedrine

Brand name: Bromaline, Brotapp, J-TanD PD, Lodrane D, Q-Tapp, Endafed, Touro A&H, Shellcap, Allent, Shellcap PD, Lodrane LD, Bromfed PD, Dallergy JR, Nalfed PD, Respahist, Iofed PD, Ultrabrom PD, Pseubrom-PD, Bromfenex PD, Bromfed, M-Hist TD, Ultrabrom, Iofed, Pseubrom, Bromfenex, Lodrane Liquid, Nalfed, Rondec Chewable, Touro Allergy, Rondec Syrup, Bromfed SR, Histex SR, Rondec, Andehist NR Syrup, Dimetapp Elixir, Bromaxefed RF Syrup, Brofed, Sildec, Bromhist Pediatric Drops, Lodrane 12D, AccuHist Pediatric, AccuHist Drops, Unit-Tex 10/120 ER, Unit-Hist Drops, Di-Bromm, Bromhist-NR, Bidhist-D, Dimaphen, Brovex SR, Lodrane 24D, LoHist-PD, LoHist-12D, B-Vex PD, BroveX PSE, BroveX PD, BroveX PSB, LoHist PSB

Synonyms: n.a.

What is Brotapp?

Treprostinil Extended-Release Tablets

Generic Name: treprostinil

Brand name: Orenitram, Remodulin, Tyvaso, Tyvaso Refill Kit, Tyvaso Starter Kit

Synonyms: Treprostinil

What is Treprostinil Extended-Release Tablets?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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