Bumex oral/injection and Magnesium Hydroxide and Mineral Oil
Determining the interaction of Bumex oral/injection and Magnesium Hydroxide and Mineral Oil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using bumetanide together with any kind of medication that has a laxative effect. Combining these medications, especially over a prolonged period, may increase the risk of dehydration and electrolyte abnormalities. In severe cases, dehydration and electrolyte abnormalities can lead to irregular heart rhythm, seizures, and kidney problems. You should use magnesium hydroxide exactly as prescribed by your doctor or as directed on the label of the medication. Contact your doctor if you experience potential signs and symptoms of fluid and electrolyte depletion such as dizziness, lightheadedness, dry mouth, thirst, fatigue, weakness, muscle cramps, decreased urination, palpitation, and increased heart rate. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes, including sodium, potassium, magnesium and zinc, and these effects may be additive to those of diuretics.
MANAGEMENT: In general, laxatives should only be used on a short-term, intermittent basis in recommended dosages. During concomitant use with diuretics, patients should be advised to contact their physician if they experience signs and symptoms of fluid and electrolyte depletion such as dizziness, lightheadedness, dry mouth, thirst, fatigue, weakness, lethargy, muscle cramps, decreased urination, postural hypotension, and tachycardia. If maintenance of bowel regularity is required, patients should be advised to exercise and increase fiber in the diet and/or consider the use of bulk-forming laxatives.
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- Muller-Lissner SA "Adverse effects of laxatives: fact and fiction." Pharmacology 47 (1993): 138-45
- Leary WP, Reyes AJ "Drug interactions with diuretics." S Afr Med J 65 (1984): 455-61
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Generic Name: bumetanide
Brand name: Bumex
Synonyms: Bumex (oral/injection), Bumex
Generic Name: magnesium hydroxide / mineral oil
Brand name: Phillips' M-O
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bumex oral/injection-Magnesium Hydroxide Chewable Tablets
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- Bumex oral/injection-Magnesium L-Aspartate Hydrochloride Powder Packets
- Bumex oral/injection-Magnesium L-Aspartate Hydrochloride Tablets
- Bumex oral/injection-Magnesium L-lactate
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- Magnesium Hydroxide and Mineral Oil-Bunavail
- Magnesium Hydroxide and Mineral Oil-Bunavail Buccal Film
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- Magnesium Hydroxide and Mineral Oil-Bupap Tablets
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