Bumex oral/injection and Methylphen Tablets
Determining the interaction of Bumex oral/injection and Methylphen Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Salicylates in anti-inflammatory dosages may blunt the diuretic and natriuretic response to loop diuretics. The interaction has been demonstrated in patients with ascites secondary to liver cirrhosis and in normal volunteers. Investigators theorize that salicylates may inhibit the renal effects of loop diuretics that are mediated by prostaglandins, including increases in sodium excretion, renal blood flow, and plasma renin activity. Since renal prostaglandins are believed to play a major role in the maintenance of renal blood flow and glomerular filtration rate in cirrhotics with ascites, the interaction may be particularly important in this population. No clinical interventions are generally required, but the possibility of a potential interaction should be considered in patients with ascites treated with a loop diuretic and salicylate or salicylate-related product.
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- Salerno F, Lorenzano E, Maggi A, Badalamenti S, Minuz P, Degan M, Chinea B, Scotti A "Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites." J Hepatol 19 (1993): 279-84
Generic Name: bumetanide
Brand name: Bumex
Synonyms: Bumex (oral/injection), Bumex
Generic Name: benzoic acid / hyoscyamine / methenamine / methylene blue / phenyl salicylate
Brand name: Hyophen, Prosed/DS, Urophen MB
Synonyms: Methenamine, Phenyl Salicylate, Methylene Blue, Benzoic Acid, Hyoscyamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bumex oral/injection-Methylphenidate
- Bumex oral/injection-Methylphenidate CD Capsules
- Bumex oral/injection-Methylphenidate Chewable Tablets
- Bumex oral/injection-Methylphenidate Controlled-Release Tablets
- Bumex oral/injection-Methylphenidate ER Capsules
- Bumex oral/injection-Methylphenidate Extended-Release Capsules (Evening Formulation)
- Methylphen Tablets-BumP DHA
- Methylphen Tablets-Bunavail
- Methylphen Tablets-Bunavail Buccal Film
- Methylphen Tablets-Bupap
- Methylphen Tablets-Bupap Tablets
- Methylphen Tablets-Buphenyl