Bupivacaine and Epinephrine Injection and Exparel
Determining the interaction of Bupivacaine and Epinephrine Injection and Exparel and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Bupivacaine liposome and bupivacaine both contain the same medication and should generally not be used together. After treatment with bupivacaine liposome, at least 4 days (96 hours) should pass before using bupivacaine.
Professional:ADJUST DOSING INTERVAL: The use of bupivacaine liposome injectable suspension followed by other bupivacaine formulations has not been studied in clinical trials. Injection of bupivacaine hydrochloride immediately before bupivacaine liposome suspension may impact the pharmacokinetic and/or physicochemical properties of the drugs when the milligram dose of bupivacaine HCl solution exceeds 50% of the bupivacaine liposome dose.
MANAGEMENT: Other formulations of bupivacaine should not be administered within 96 hours following the administration of bupivacaine liposome injectable suspension.
- "Product Information. Exparel (bupivacaine liposome)." Pacira Pharmaceuticals Inc, San Diego, CA.
Generic Name: bupivacaine / epinephrine
Brand name: Marcaine/Epinephrine, Marcaine/Epinephrine PF, Sensorcaine-MPF/EPINEPHrine, Sensorcaine/EPINEPHrine
Synonyms: Bupivacaine and Epinephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bupivacaine and Epinephrine Injection-Expectuss Liquid
- Bupivacaine and Epinephrine Injection-Extavia
- Bupivacaine and Epinephrine Injection-Extendryl HC
- Bupivacaine and Epinephrine Injection-Extra-Virt Plus DHA
- Bupivacaine and Epinephrine Injection-Exubera
- Bupivacaine and Epinephrine Injection-Eye Allergy Relief
- Exparel-Bupivacaine Fisiopharma
- Exparel-Bupivacaine Hydrochloride
- Exparel-Bupivacaine Injection
- Exparel-Bupivacaine liposome
- Exparel-Bupivacaine liposome Injection
- Exparel-Bupivacaine Spinal