Bupivacaine and Epinephrine Injection and Quinidine Sulfate Tablets
Determining the interaction of Bupivacaine and Epinephrine Injection and Quinidine Sulfate Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One in vitro study has suggested that quinidine may displace bupivacaine from plasma protein-binding sites. Theoretically, the risk of toxicity from the local anesthetic could increase.
- Ghoneim MM, Pandya H "Plasma protein binding of bupivacaine and its interaction with other drugs in man." Br J Anaesth 46 (1974): 435-8
Generic Name: bupivacaine / epinephrine
Brand name: Marcaine/Epinephrine, Marcaine/Epinephrine PF, Sensorcaine-MPF/EPINEPHrine, Sensorcaine/EPINEPHrine
Synonyms: Bupivacaine and Epinephrine
Generic Name: quinidine
Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release
Synonyms: Quinidine, QuiNIDine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bupivacaine and Epinephrine Injection-Quinidine Tablets
- Bupivacaine and Epinephrine Injection-Quinine
- Bupivacaine and Epinephrine Injection-Quinine Sulfate
- Bupivacaine and Epinephrine Injection-Quinine Sulfate Capsules
- Bupivacaine and Epinephrine Injection-Quinja
- Bupivacaine and Epinephrine Injection-Quinja Gel
- Quinidine Sulfate Tablets-Bupivacaine Fisiopharma
- Quinidine Sulfate Tablets-Bupivacaine Hydrochloride
- Quinidine Sulfate Tablets-Bupivacaine Injection
- Quinidine Sulfate Tablets-Bupivacaine liposome
- Quinidine Sulfate Tablets-Bupivacaine liposome Injection
- Quinidine Sulfate Tablets-Bupivacaine Spinal