Bupivacaine liposome Injection and Marcaine/Epinephrine PF

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Bupivacaine liposome and bupivacaine both contain the same medication and should generally not be used together. After treatment with bupivacaine liposome, at least 4 days (96 hours) should pass before using bupivacaine.

ADJUST DOSING INTERVAL: The use of bupivacaine liposome injectable suspension followed by other bupivacaine formulations has not been studied in clinical trials. Injection of bupivacaine hydrochloride immediately before bupivacaine liposome suspension may impact the pharmacokinetic and/or physicochemical properties of the drugs when the milligram dose of bupivacaine HCl solution exceeds 50% of the bupivacaine liposome dose.

MANAGEMENT: Other formulations of bupivacaine should not be administered within 96 hours following the administration of bupivacaine liposome injectable suspension.

Bupivacaine liposome Injection

Generic Name: bupivacaine liposome

Brand name: Exparel

Synonyms: Bupivacaine liposome, Bupivacaine (Liposomal)

What is Bupivacaine liposome Injection?

Marcaine/Epinephrine PF

Generic Name: bupivacaine / epinephrine

Brand name: Marcaine/Epinephrine, Marcaine/Epinephrine PF, Sensorcaine-MPF/EPINEPHrine, Sensorcaine/EPINEPHrine

Synonyms: Marcaine/Epinephrine, Marcaine with Epinephrine

What is Marcaine/Epinephrine PF?