Buprenorphine and Naloxone Sublingual Film (Suboxone) and Hyoscyamine Sulfate Elixir
Determining the interaction of Buprenorphine and Naloxone Sublingual Film (Suboxone) and Hyoscyamine Sulfate Elixir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using buprenorphine together with hyoscyamine can increase the effects of either medication. This can commonly cause dizziness, drowsiness, difficulty concentrating, dry mouth, abdominal cramping, and constipation. Some people may also experience some impairment in thinking and judgment. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of narcotic analgesics with anticholinergic agents may result in additive central nervous system (CNS) and gastrointestinal (GI) adverse effects, and increase the risk of severe constipation or paralytic ileus and CNS depression.
MANAGEMENT: If concomitant use cannot be avoided, patients should be monitored for potentially excessive or prolonged CNS depression and constipation. Ambulatory patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: buprenorphine / naloxone
Brand name: Bunavail, Suboxone, Zubsolv
Synonyms: Buprenorphine and naloxone (oral/sublingual), Buprenorphine and Naloxone
Generic Name: hyoscyamine
Brand name: Anaspaz, Ed Spaz, Hyosyne, Levbid, Levsin, NuLev, Symax SR, Cystospaz, Levsin SL, Cystospaz-M, Levsinex SR, Symax SL, A-Spas S/L, Donnamar, Hyosol, NuLev, Spasdel, IB-Stat, Hyospaz, Symax Duotab, Symax FasTab, HyoMax SL, HyoMax SR, HyoMax FT, HyoMax DT, HyoMax, Oscimin, A-Spaz, Levsin/SL, Colidrops, Levsinex, Symax, Symax FasTabs
Synonyms: Hyoscyamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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