Buprenorphine implant and Xyntha

• Generic Name: buprenorphine
• Dosage Forms: n.a.
• Other Brand Names: Probuphine, Belbuca, Buprenex, Butrans, Sublocade, Subutex

Buprenorphine implant (placed under the skin) is used to treat opioid addiction in certain people whose addiction has already been controlled with other forms of buprenorphine. The implant is for adults and teenagers who are at least 16 years old.

Buprenorphine implants are available only from a certified pharmacy under a special program. Buprenorphine implants are not for use as a pain medication.

Buprenorphine implants may also be used for purposes not listed in this medication guide.

• Generic Name: antihemophilic factor
• Dosage Forms: injection
• Other Brand Names: Advate, Adynovate, Afstyla, Eloctate with Fc Fusion Protein, Helixate FS, Kogenate FS, Kovaltry, Novoeight, Nuwiq, Recombinate, Xyntha, Hemofil-M, Koate-DVI, Monoclate-P, Jivi, Obizur

Xyntha contains recombinant antihemophilic factor. Antihemophilic factor is a naturally occurring protein in the blood that helps blood to clot. A lack of antihemophilic factor VIII is the cause of hemophilia A.

Xyntha works by temporarily raising levels of factor VIII in the blood to aid in clotting.

Xyntha is used to treat or prevent bleeding episodes in adults and children with hemophilia A. It is also used to control bleeding related to surgery or dentistry in a person with hemophilia, and to prevent joint damage in people age 16 or older with severe hemophilia A and no prior joint damage.

Xyntha is not for use in people with von Willebrand disease.