Buprenorphine/naloxone Oromucosal, Sublingual and Naltrexone Hydrochloride And Bupropion Hydrochloride

• Generic Name: buprenorphine / naloxone
• Dosage Forms: n.a.
• Other Brand Names: Bunavail, Suboxone, Zubsolv

Buprenorphine and naloxone sublingual tablet is used to treat opioid (narcotic) dependence or addiction. Buprenorphine and naloxone buccal film, sublingual film, or sublingual tablet is used for induction and maintenance treatment of opioid (narcotic) dependence. It should be used in patients who have already been treated with buprenorphine sublingual tablets.

When a narcotic medicine is used for a long time, it may become habit-forming, causing mental or physical dependence. Physical dependence may lead to withdrawal side effects if the narcotic is stopped suddenly. Severe withdrawal side effects can usually be prevented when a person is switched to buprenorphine and naloxone combination. It acts on the central nervous system (CNS) to help prevent the withdrawal side effects.

Buprenorphine/naloxone is available only with your doctor's prescription.

• Generic Name: bupropion / naltrexone
• Dosage Forms: n.a.
• Other Brand Names: Contrave

Naltrexone hydrochloride and bupropion hydrochloride is a fixed combination of naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant, and is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

The effect of naltrexone hydrochloride and bupropion hydrochloride on cardiovascular morbidity and mortality has not been established.

The safety and effectiveness of naltrexone hydrochloride and bupropion hydrochloride in combination with other products intended for weight loss, including prescription and over-the-counter drugs and herbal preparations, have not been established.