Bupropion SR Tablets and Nicotrol Inhalation, oral/nebulization
Determining the interaction of Bupropion SR Tablets and Nicotrol Inhalation, oral/nebulization and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using buPROPion and nicotine together can cause an increase in blood pressure. This can cause dizziness, confusion, uneven heartbeats, and chest pain. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of bupropion and nicotine replacement for smoking cessation may increase the risk of hypertension. In a clinical study (n=250), 6.1% of patients who used sustained-release bupropion with nicotine transdermal system developed treatment-emergent hypertension, compared to 2.5% of patients treated with bupropion alone, 1.6% treated with nicotine alone, and 3.1% treated with placebo. Three patients in the bupropion plus nicotine group and one patient in the nicotine-only group discontinued treatment due to hypertension. The majority had evidence of preexisting hypertension.
MANAGEMENT: Blood pressure monitoring is recommended for patients concomitantly using bupropion and nicotine replacement for smoking cessation.
- "Product Information. Zyban (bupropion)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: bupropion
Brand name: Aplenzin, Buproban, Forfivo XL, Wellbutrin SR, Wellbutrin XL, Zyban, Zyban Advantage Pack, Budeprion XL
Synonyms: Bupropion, BuPROPion
Generic Name: nicotine
Brand name: Nicotrol Inhaler, Nicotrol NS, Commit, Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ
Synonyms: Nicotrol Inhaler (nasal, inhalation), Nicotrol Inhalant
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Bupropion SR Tablets-Nicotrol Inhaler
- Bupropion SR Tablets-Nicotrol Inhaler nasal, inhalation
- Bupropion SR Tablets-Nicotrol NS
- Bupropion SR Tablets-Nicotrol NS nasal, inhalation
- Bupropion SR Tablets-Nicotrol Oral, Transdermal
- Bupropion SR Tablets-Nidagel
- Nicotrol Inhalation, oral/nebulization-Bupropion Sustained-Release Tablets (Smoking Deterrent)
- Nicotrol Inhalation, oral/nebulization-Bupropion Tablets
- Nicotrol Inhalation, oral/nebulization-Bupropion Tablets and Sustained-Release Tablets
- Nicotrol Inhalation, oral/nebulization-Burapren Injection
- Nicotrol Inhalation, oral/nebulization-Burn-O-Jel Topical application
- Nicotrol Inhalation, oral/nebulization-Burnamycin Topical application