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Burapren Injection and Lymphoseek

Determining the interaction of Burapren Injection and Lymphoseek and the possibility of their joint administration.

Check result:
Burapren Injection <> Lymphoseek
Relevance: 28.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Tilmanocept should not be mixed or coadministered with bupivacaine or other local anesthetics due to potential impairment of lymph nodal mapping.

Professional:

GENERALLY AVOID: Locally injected anesthetics have been reported to reduce lymphatic flow of Technetium Tc 99m tilmanocept in animal studies.

MANAGEMENT: Co-injection (mixture) of local anesthetics with Technetium Tc 99m tilmanocept is not recommended due to potential impairment of lymph nodal mapping.

References
  • "Product Information. Lymphoseek (tilmanocept)." Navidea Biopharmaceuticals, Dublin, OH.
Burapren Injection

Generic Name: bupivacaine

Brand name: Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF, Sensorcaine-MPF Spinal, Bupivacaine Fisiopharma, Bupivacaine Spinal, Marcaine, Marcaine Preservative Free, P-Care M, ReadySharp Bupivacaine

Synonyms: Bupivacaine

Lymphoseek

Generic Name: tilmanocept

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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