Burosumab-twza and Etelcalcetide Hydrochloride

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using burosumab together with etelcalcetide may cause a condition known as hypocalcemia, or low blood calcium. Symptoms of hypocalcemia include numbness or tingling around your mouth, muscle spasms, convulsions, mental changes (irritability, depression, psychosis), increased pressure on the brain, and irregular heartbeat. Let your doctor know if you experience these or other unusual symptoms. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of burosumab with calcimimetic drugs, such as cinacalcet, may potentially exacerbate hypocalcemia. The mechanism for this interaction has not been delineated.

MANAGEMENT: Until further information is available, caution is advised when combining burosumab with calcimimetic drugs.

Burosumab-twza

Generic Name: burosumab

Brand name: Crysvita

Synonyms: Burosumab

What is Burosumab-twza?

Etelcalcetide Hydrochloride

Generic Name: etelcalcetide

Brand name: Parsabiv

Synonyms: Etelcalcetide

What is Etelcalcetide Hydrochloride?