Busulfan Concentrate Injection and Lyme disease vaccine (recombinant ospa) Intramuscular
Determining the interaction of Busulfan Concentrate Injection and Lyme disease vaccine (recombinant ospa) Intramuscular and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:If you are currently being treated or have recently been treated with busulfan, you should let your doctor know before receiving Lyme disease vaccine. Depending on the dose and length of time you have been on busulfan, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of busulfan therapy. If you have recently been vaccinated with Lyme disease vaccine, your doctor may choose to postpone treatment with busulfan for a couple of weeks. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The administration of Lyme disease vaccine to immunosuppressed patients may be associated with a diminished or suboptimal immunologic response due to antibody inhibition. Such patients may include those who have recently received or are receiving immunosuppressive agents, antilymphocyte globulins, alkylating agents, antimetabolites, radiation, some antirheumatic agents, high dosages of corticosteroids or adrenocorticotropic agents (greater than 10 mg/day to 1 mg/kg/day, whichever is less, of prednisone or equivalent for more than 2 weeks), or long-term topical or inhaled corticosteroids.
MANAGEMENT: The manufacturer suggests considering deferral of vaccination against Lyme disease until 3 months after discontinuation of immunosuppressive therapy. Vaccines may generally be administered to patients receiving corticosteroids as replacement therapy (e.g., for Addison's disease).
- "Product Information. Lymerix (Lyme disease vaccine)." SmithKline Beecham, Philadelphia, PA.
Generic Name: busulfan
Brand name: Busulfex, Myleran
Synonyms: Busulfan (oral/injection), Busulfan
Generic Name: lyme disease vaccine
Brand name:
Synonyms: Lyme disease vaccine (recombinant ospa)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Busulfan Concentrate Injection-Lynparza (Olaparib Capsules)
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- Lyme disease vaccine (recombinant ospa) Intramuscular-Busulfan Intravenous
- Lyme disease vaccine (recombinant ospa) Intramuscular-Busulfan oral/injection
- Lyme disease vaccine (recombinant ospa) Intramuscular-Busulfan Tablet
- Lyme disease vaccine (recombinant ospa) Intramuscular-Busulfex
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