Busulfan Intravenous and Incobotulinumtoxina Intramuscular

• Generic Name: busulfan
• Dosage Forms: n.a.
• Other Brand Names: Busulfex, Myleran

Busulfan injection is used in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for treatment of chronic myelogenous leukemia.

Busulfan belongs to the group of medicines known as alkylating agents. It seems to act by interfering with the function of the bone marrow. Since the growth of normal body cells may also be affected by busulfan, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with busulfan, you and your doctor should talk about the benefits busulfan will do as well as the risks of using it.

Busulfan is to be given only by or under the direct supervision of your doctor.

• Generic Name: incobotulinumtoxinA
• Dosage Forms: n.a.
• Other Brand Names: Xeomin

IncobotulinumtoxinA is used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). It is also used to treat upper limb spasticity (muscle spasms in the upper arms). Incobotulinumtoxina is also used to treat a certain eye condition called blepharospasm (a condition where the eyelid will not stay open because of a muscle spasm) in patients who have already been treated with onabotulinumtoxinA (Botox®). It is also used to treat long-lasting sialorrhea (excessive drooling). IncobotulinumtoxinA is also used cosmetically to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines).

IncobotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.

Incobotulinumtoxina is available only with your doctor's prescription and will be given by your doctor.